Publicações

Iva L. R. Fernandes, Nuno Filipe de Sousa Vale, Victor A. P. Freitas, Rui Moreira, Nuno F. C. B. Mateus, Paula Gomes

Anti-tumoral activity of imidazoquines, a new class of antimalarials derived from primaquine.

Bioorganic and Medicinal Chemistry Letters, Vol.19,
Pages 6914-6917, 2009

Nuno F. S. Vale, Joana Matos, Rui Moreira, Paula Gomes

Electrospray ionization mass spectrometry as a valuable tool in the characterization of novel primaquine peptidomimetic derivatives.

European Journal of Mass Spectrometry, Vol.15,
Pages 627-640, 2009

Mary K. S. Batista, Alberto Adeva, Marçal Gallemí, Carlos Rocha Gomes, Paula Gomes

Facile regiosselective synthesis of a novel Chitosan-Pexiganan conjugate with potential interest for the treatment of infected skin lesions.

Synthetic Communications, Vol.39,
Pages 1228-1240, 2009

Nuno Filipe de Sousa Vale, Miguel Prudêncio, Margaret Collins, Fátima Nogueira, Joana Matos, Phil Rosenthal, Melanie Cushion, Virgílio do Rosário, Rui Moreira, Paula Gomes

Imidazoquines as antimalarial and anti-pneumocystis agents.

Journal of Medicinal Chemistry, Vol.ahead of print, doi: 10.1021/jm900738c,
2009

Joana Matos, Nuno Filipe de Sousa Vale, Rui Moreira, Paula Gomes

On the activation of ferrocenecarboxylic acid with current in situ peptide coupling agents: towards ferrocene-primaquine conjugates.

Journal of Organometallic Chemistry, Vol.under revision,
2009

Rodrigo O. Brito, Eduardo F. Marques, Sandra Silva, Maria J. S. M. P. Araújo, Maria L. C. Vale, Paula Gomes, José E. R. Borges, et al.

Physicochemical and biological properties of novel amino-acid based amphiphiles and their catanionic liposomes

Colloids and Surfaces B: Biointerfaces, Vol.72,
Pages 80–87, 2009

Nuno F. S. Vale, Luís Gouveia, Rui Moreira, Paula Gomes

Primaquine dipeptide derivatives bearing an imidazolidin-4-one at the N-terminus as potential antimalarial prodrugs

European Journal of Medicinal Chemistry, Vol.44,
Pages 2506-2516, 2009

Nuno F. S. Vale, Rui Moreira, Paula Gomes

Primaquine revisited six decades after its discovery

European Journal of Medicinal Chemistry, Vol.44,
Pages 937-953, 2009

Fernanda Marques, Lurdes Gano, Mary K. S. Batista, Carlos Rocha Gomes, Paula Gomes, Isabel R. Santos

Radiochemical and biological evaluation of novel 153Sm/166Ho-peptide-chitosan complexes for tumour radionuclide therapy.

Journal of Labelled Compounds and Radiopharmaceuticals, Vol.52,
Pages 79-83, 2009

Cledir R. Santos, Rita Capela, Cláudia Pereira, Carsten U. Nielsen, Erik de Clercq, Rui Moreira, Paula Gomes

Structure-activity relationships for dipeptide prodrugs of acyclovir: implications for prodrug design.

European Journal of Medicinal Chemistry, Vol.44,
Pages 2339-2346, 2009

Jose R. B. Gomes, André Monteiro, Bruno José Brandão Campos, Paula Gomes, Maria D. M. C. Ribeiro da Silva

The enthalpies of dissociation of the N-O bonds in two quinoxaline derivatives

Journal of Physical Organic Chemistry, Vol.22,
Pages 17-23, 2009

Joana Matos, Nuno F. S. Vale, Rui Moreira, Paula Gomes

Towards dual-action antimalarials - Primacenes, ferrocenic derivatives of primaquine

Drugs of the Future, 34 (Suppl. A), 71, 2009

Paula Gomes, Maria J. S. M. P. Araújo, Eduardo F. Marques, Soraia Falcão, Rodrigo O. Brito

A straightforward method for the preparation of lysine-based double-chained anionic surfactants.

Synthetic Communications, Vol.38,
Pages 2013-2024, 2008

Nuno F. S. Vale, Rui Moreira, Paula Gomes

Amino acids as selective acylating agents: regiosselective N1-acylation of imidazolidin-4-one derivatives of the antimalarial drug primaquine.

Tetrahedron, Vol.64,
Pages 11144-11149, 2008

Nuno F. S. Vale, Margaret Collins, Jiri Gut, Phil Rosenthal, Melanie Cushion, Rui Moreira, Paula Gomes

Anti-Pneumocystis carinii and antiplasmodial activities of primaquine-derived imidazolidin-4-ones.

Bioorganic and Medicinal Chemistry Letters, Vol.18,
Pages 485-488, 2008

Nuno F. S. Vale, Rui Moreira, Paula Gomes

Characterization of primaquine imidazolidin-4-ones with antimalarial activity by electrospray ionization-ion trap mass spectrometry.

International Journal of Mass Spectrometry, Vol.270,
Pages 81-93, 2008

Magda Valldosera, Marta Monsó, Paula D. Raposinho, João D. G. Correia, Isabel R. Santos, Paula Gomes

Comparative study of chemical approaches to the solid-phase synthesis of a tumor-seeking alpha-MSH analogue

International Journal of Peptide Research and Therapeutics, Vol.14,
Pages 273-281, 2008

Cledir R. Santos, José Morais, Luís Gouveia, Erik de Clercq, Cristophe Pannecouque, Carsten U. Nielsen, Bente Steffansen, Rui Moreira, Paula Gomes

Dipeptide derivatives of AZT: synthesis, chemical stability, activation in human plasma, hPEPT1 affinity and antiviral activity

ChemMedChem, Vol.3,
Pages 970-978, 2008

Nuno F. S. Vale, Joana Matos, Rui Moreira, Paula Gomes

Electrospray ionization-ion trap mass spectrometry study of PQAAPro and PQProAA mimetic derivatives of the antimalarial primaquine

Journal of the American Society for Mass Spectrometry, Vol.19,
Pages 1476-1490, 2008

Margarida Bastos, Guangyue W. Bai, Paula Gomes, David Andreu, Erik Goormaghtigh, Manuel Prieto

Energetics and partition of two cecropin-melittin hybrid peptides to model membranes of different composition

Biophysical Journal, Vol.94,
Pages 2128-2141, 2008

Nuno F. S. Vale, Joana Matos, Jiri Gut, Fátima Nogueira, Virgílio do Rosário, Phil Rosenthal, Rui Moreira, Paula Gomes

Imidazolidin-4-one peptidomimetic derivatives of primaquine: synthesis and antimalarial activity.

Bioorganic and Medicinal Chemistry Letters, Vol.18,
Pages 4150-4153, 2008

Paula D. Raposinho, Catarina Xavier, João D. G. Galamba, Soraia Falcão, Paula Gomes, Isabel R. Santos

Melanoma targeting with alpha-melanocyte stimulating hormone analogs labeled with fac-[99mTc(CO)3]+: Effect of cyclization on tumor-seeking properties.

Journal of Biological Inorganic Chemistry, Vol.13,
Pages 449-459, 2008

Regina C. Adão, Raquel Seixas, Paula Gomes, João Pessoa, Margarida Bastos

Membrane structure and interactions of a short Lycotoxin I analogue

Journal of Peptide Science, Vol.14,
Pages 528-534, 2008

S. Trabulo, M. Mano, H. Faneca, A. L. Cardoso, S. Duarte, A. Paiva, Paula Gomes, S. Simões, M. C. Pedroso de Lima

S413-PV cell penetrating peptide and cationic liposomes act synergistically for the intracellular delivery of plasmid DNA.

Journal of Gene Medicine, Vol.10,
Pages 1210-1222, 2008

Eduardo F. Marques, Rodrigo O. Brito, Sandra Silva, Maria L. C. Vale, José E. R. Borges, Paula Gomes, Maria J. S. M. P. Araújo, Olle Söderman

Spontaneous vesicle formation in catanionic mixtures of amino acid-based surfactants: Chain length symmetry effects

Langmuir, Vol.24,
Pages 11009-11017, 2008

Rodrigo O. Brito, Eduardo F. Marques, Paula Gomes, Maria J. S. M. P. Araújo, R. Pons

Structure/property relationships for the thermotropic behavior of lysine-based amphiphiles: from hexagonal to smectic phases.

Journal of Physical Chemistry B, Vol.112,
Pages 14877-14887, 2008

Paula Gomes, Carlos Rocha Gomes, Mary K. S. Batista, Luiz F. Pinto, Paulo A. P. Silva

Synthesis, structural characterization and properties of water-soluble N-(gamma-propanoyl-amino acid)-chitosans.

Carbohydrate Polymers, Vol.71,
Pages 54-65, 2008

S. Trabulo, M. Mano, H. Faneca, A. L. Cardoso, S. Duarte, Paula Gomes, S. Simões, M. C. Pedroso de Lima

Association of S4(13)-PV cell penetrating peptide with cationic liposomes: a synergistic effect on the intracellular delivery of plasmid DNA.

Journal of Peptide Science 14 (Suppl), 135, 2008

Marçal Gallemí, Alberto Adeva, Mary K. S. Batista, Carlos Rocha Gomes, Paula Gomes

Novel chitosan-pexiganan conjugate for the treatment of infected diabetic foot ulcers: synthesis and characterization by FT-IR and amino acid analysis.

Journal of Peptide Science 14 (Suppl), 105, 2008

Nuno F. S. Vale, Francisca Lopes, Miguel Prudêncio, Jiri Gut, Margaret Collins, Melanie Cushion, Phil Rosenthal, Maria M. Mota, Rui Moreira, Paula Gomes

Peptidomimetic derivatives of primaquine as promising leads against malaria and other primaquine-susceptible diseases.

Revista Portuguesa de Farmácia, LII (nº 3, supl), 41., 2008

Nuno F. S. Vale, Miguel Prudêncio, Maria M. Mota, Joana Matos, Rui Moreira, Paula Gomes

Peptidomimetic derivatives of primaquine as promising tissue-schizontocidal antimalarials.

Revista Portuguesa de Farmácia, LII (nº 3, supl.), 175, 2008

Nuno F. S. Vale, Joana Matos, Margaret Collins, Melanie Cushion, Rui Moreira, Paula Gomes

Peptidomimetic derivatives of primaquine with anti-Pneumocystis carinii activity.

Revista Portuguesa de Farmácia, LII (nº 3, supl), 176., 2008

Nuno F. S. Vale, Joana Matos, Jiri Gut, Fátima Nogueira, Phil Rosenthal, Virgílio do Rosário, Rui Moreira, Paula Gomes

Synthesis and antimalarial activity of imidazolidin-4-one peptidomimetic derivatives of primaquine.

Drugs of the Future, 33 (Suppl. A), 51, 2008

Nuno F. S. Vale, Rui Moreira, Paula Gomes

Synthesis and reactivity of dipeptide imidazolidin-4-one derivatives of primaquine as potential antimalarial prodrugs.

Drugs of the Future, 33 (Suppl. A), 51., 2008

Nuno F. S. Vale, Rui Moreira, Paula Gomes

Cyclization-activated prodrugs.

Molecules, Vol.12,
Pages 2484-2506, 2007

Jose R. B. Gomes, Emanuel A. Sousa, Jorge M. Gonçalves, Luís Gales, Ana M. Damas, Paula Gomes, Siddarth Pandey, William E. Acree, Jr., Maria D. M. C. Ribeiro da Silva

Energetic and structural characterization of 2-R-3-methylquinoxaline-1,4-dioxides (R=benzoyl or tert-butoxycarbonyl): experimental and computational studies.

Journal of Physical Organic Chemistry, Vol.20,
Pages 491-498, 2007

Jose R. B. Gomes, Emanuel A. Sousa, Paula Gomes, Nuno F. S. Vale, Jorge M. Gonçalves, Siddarth Pandey, William E. Acree, Jr., Maria D. M. C. Ribeiro da Silva

Thermochemical studies on 3-methyl-quinoxaline-2-carboxamide-1,4-dioxide derivatives: enthalpies of formation and of N-O bond dissociation.

Journal of Physical Chemistry B, Vol.111,
Pages 2075-2080, 2007

Ricardo Ferraz, Jose R. B. Gomes, Eliandre de Oliveira, Rui Moreira, Paula Gomes

Unanticipated stereoselectivity in the reaction of primaquine alpha-aminoamides with substituted benzaldehydes: computational and experimental study.

Journal of Organic Chemistry, Vol.72,
Pages 4189-4197, 2007

Rodrigo O. Brito, Eduardo F. Marques, Paula Gomes, Maria J. S. M. P. Araújo, Olle Söderman, M. R. Infante, M. T. García, P. Vinardell, M. Mitjans

Spontaneous vesicle formation in a catanionic mixture with a lysine-derived surfactant: phase behavior, structural and toxicity studies.

Proceedings of the RICI2 - IIª Reunião Ibérica de Colóides e Interfaces/VIII Reunión del Grupo Especializado de Coloides e Interfases de las Reales Sociedades de Química y Física
Coimbra,
Pages 129-140, 2007

Nuno F. S. Vale, Rita Capela, Virgílio do Rosário, Rui Moreira, Paula Gomes

New imidazolidin-4-ones based on dipeptide derivatives of primaquine as potential prodrugs for antimalarial therapy.

Farmacevstki Vestnik, 58, 195, 2007

Manuel A. V. Ribeiro da Silva, Joana I. T. A. Cabral, Paula Gomes, Jose R. B. Gomes

Combined experimental and computational study of the thermochemistry of methylpiperidines.

Journal of Organic Chemistry, Vol.71,
Pages 3677-3685, 2006

H. D. Middendorf, J.-M. Zanotti, Paula Gomes, Margarida Bastos

Dynamics of an antibiotic oligopeptide.

Physica B, Vol.385-386,
Pages 874-876, 2006

Mary K. S. Batista, Luiz F. Pinto, Carlos Rocha Gomes, Paula Gomes

Novel highly-soluble peptide-chitosan polymers: chemical synthesis and spectral characterization.

Carbohydrate Polymers, Vol.64,
Pages 299-305, 2006

Paula Chambel, Rita Capela, Francisca Lopes, Jim Iley, José Morais, Luís Gouveia, Jose R. B. Gomes, Paula Gomes, Rui Moreira

Reactivity of imidazolidin-4-one derivatives of primaquine: implications for prodrug design.

Tetrahedron, Vol.62,
Pages 9883-9891, 2006

Rodrigo O. Brito, Eduardo F. Marques, Paula Gomes, Soraia Falcão, Olle Söderman

Self-assembly in a catanionic mixture with an aminoacid-derived surfactant: from mixed micelles to spontaneous vesicles.

Journal of Physical Chemistry B, Vol.110,
Pages 18158-18165, 2006

Nuno F. S. Vale, Soraia Falcão, Paula Gomes

Métodos Separativos e Espectroscópicos em Química Orgânica – Aulas práticas 2006

guião de laboratório para alunos do 3º ano da Licenciatura em Química, Departamento de Química da Faculdade de Ciências do Porto, 2006

Nuno F. S. Vale, Ricardo Ferraz, Joana Azevedo, Maria J. S. M. P. Araújo, Rui Moreira, Margaret Collins, Melanie Cushion, Paula Gomes

Anti-Pneumocystis carinii activity of primaquine imidazolidin-4-ones.

Drugs of the Future, 31 (Suppl. A), 56, 2006

Cledir R. Santos, Rui Moreira, Paula Gomes

Dipeptide ester prodrugs of AZT: synthesis and in vitro stability.

Drugs of the Future, 31 (Suppl. A), 212, 2006

Guangyue W. Bai, Paula Gomes, Raquel Seixas, Mathew Hicks, Manuel Prieto, Margarida Bastos

Insights on the interactions between two cecropin-melittin peptides and model membranes: calorimetric and spectroscopic results.

Journal of Peptide Science, 12 (Suppl), 156, 2006

J. R. Luque-Ortega, Paula Gomes, Raquel Seixas, Luis Rivas, David Andreu

Leishmanicidal activity of antimicrobial peptides from the wolf spider Lycosa carolinensis.

Journal of Peptide Science, 12 (Suppl), 212, 2006

Cledir R. Santos, Maria Luísa Mateus, Ana Paula Santos, Eliandre de Oliveira, Rui Moreira, Paula Gomes

Cyclization-activated prodrugs. Synthesis, reactivity and toxicity of dipeptide esters of paracetamol.

Bioorganic and Medicinal Chemistry Letters, Vol.15,
Pages 1595-1598, 2005

Jose R. B. Gomes, Paula Gomes

Gas-phase acidity of sulfonamides: implications for reactivity and prodrug design.

Tetrahedron, Vol.61,
Pages 2705-2712, 2005

Maria J. S. M. P. Araújo, Joana Bom, Rita Capela, Catarina Casimiro, Paula Chambel, Paula Gomes, Jim Iley, et al.

Imidazolidin-4-ones of primaquine as novel transmission-blocking antimalarials.

Journal of Medicinal Chemistry, Vol.48,
Pages 888-892, 2005

Filipa Abrunhosa, Sílvia Faria, Paula Gomes, Isabel Thomaz, João Pessoa, David Andreu, Margarida Bastos

Interaction and lipid-induced conformation of two cecropin-melittin hybrid peptides depends on peptide and membrane composition.

Journal of Physical Chemistry B, Vol.109,
Pages 17311-17319, 2005

Nuno F. S. Vale, Rui Moreira, Paula Gomes

Quimioterapia da malária – um século no desenvolvimento de antimaláricos.

Química, Vol.99,
Pages 61-73, 2005

Cledir R. Santos, Rui Moreira, Paula Gomes

Cyclization-activated prodrugs: dipeptide esters of paracetamol .

Peptides 2004 - Proceedings of the 28th European Peptide Symposium
M. Flegel (Editor), M. Fridkin (Editor), C. Gilon (Editor), J. Slaninova (Editor), Kenes International,
Pages 938-939, 2005

Victor A. P. Freitas, Maria J. S. M. P. Araújo, Maria L. C. Vale, José E. R. Borges, Fátima Paiva-Martins, Nuno F. C. B. Mateus, Paula Gomes

Química dos Alimentos – Guião Prático

manual de laboratório para os formandos da Acção de Formação CCPCF/DC-5861/03, Departamento de Química da Faculdade de Ciências do Porto, 2005

Margarida Bastos, Filipa Abrunhosa, Guangyue W. Bai, Paula Gomes, David Andreu, Manuel Prieto

Interaction and lipid-induced conformation of two cecropin-melittin hybrid peptides.

European Biophysics Journal, 34(6), 692, 2005

Cláudia Pereira, Cledir R. Santos, João Barreira, Rui Moreira, Isabel Ferreira, Letícia Estevinho, Paula Gomes

Synthesis and antimicrobial activity of dipeptide esters of the anti-retroviral drug acyclovir.

Scientia Pharmaceutica, 73(2), S133, 2005

Cledir R. Santos, Rui Moreira, Bente Steffansen, C. U. Nielsen, Paula Gomes

Synthesis of dipeptide esters of AZT and their interaction with the hPEPT1 oligopeptide transporter.

Scientia Pharmaceutica, 73(2), S134, 2005

E. Escribano-Romero, M. A. Jiménez-Clavero, Paula Gomes, J. A. García-Ranea, Victoria Ley

Heparan sulphate mediates swine vesicular disease virus attachment to the host cell.

Journal of General Virology, Vol.85,
Pages 653-663, 2004

Paula Gomes, Maria J. S. M. P. Araújo, Manuela Rodrigues, Nuno F. S. Vale, Zélia M. B. S. Azevedo, Jim Iley, Paula Chambel, José Morais, Rui Moreira

Synthesis of imidazolidin-4-one and 1H-imidazo[2,1-a]isoindole-2,5(3H,9bH)-dione derivatives of primaquine: scope and limitations.

Tetrahedron, Vol.60,
Pages 5551-5562, 2004

Paula Gomes

Métodos Separativos e Espectroscópicos em Química Orgânica

manual de trabalhos práticos, 3º ano da Licenciatura em Química, Departamento de Química da Faculdade de Ciências do Porto, 2004

Paula Gomes

Química - Actividades laboratoriais

manual de trabalhos práticos para o 1º ano da Licenciatura em Biologia, Departamento de Química da Faculdade de Ciências do Porto, 2004

Victor A. P. Freitas, Maria J. S. M. P. Araújo, Maria L. C. Vale, José E. R. Borges, Fátima Paiva-Martins, Nuno F. C. B. Mateus, Paula Gomes

Química dos Alimentos – Guião Prático

manual de laboratório para os formandos da Acção de Formação CCPCF/DC-5861/03, Departamento de Química da Faculdade de Ciências do Porto, 2004

Paula Gomes, David Andreu, Guangyue W. Bai, Margarida Bastos

Calorimetric studies of the interactions of two hybrid peptides (cecropin/melittin) with liposomes.

Journal of Peptide Science, 10 (Suppl), S219, 2004

Cledir R. Santos, Rui Moreira, Paula Gomes

Cyclization-activated prodrugs: dipeptide esters of paracetamol.

Journal of Peptide Science, 10 (Suppl), S540, 2004

Paula Gomes, Jose R. B. Gomes, Manuela Rodrigues, Rui Moreira

Amino acids as selective sulfonamide acylating agents.

Tetrahedron, Vol.59,
Pages 7473-7480, 2003

Paula Gomes, Maria I. A. O. Santos, Maria Joaquina Amaral-Trigo, Raquel Castanheiro, Rui Moreira

Improved synthesis of amino acid and dipeptide chloromethyl esters using bromochloromethane.

Synthetic Communications, Vol.33,
Pages 1683-1693, 2003

Raquel Castanheiro, Maria J. S. M. P. Araújo, Ricardo Ferraz, Rui Moreira, Paula Gomes

Peptide 4-imidazolidinones as drug delivery systems.

Peptides 2002 - Proceedings of the 27th European Peptide Symposium
E. Bennedetti (Editor), C. Pedone (Editor), Edizioni Ziino, Nápoles,
Pages 936-937, 2003

Paula Gomes

Química

manual de trabalhos práticos para o 1º ano da Licenciatura em Biologia, Departamento de Química da Faculdade de Ciências do Porto, 2003

Margarida Bastos, Filipa Abrunhosa, Paula Gomes, Sílvia Faria, David Andreu

DSC study of the interactions between two hybrid peptides and DMPC and DMPG liposomes.

European Biophysics Journal, 32(3), 205, 2003

Paula Gomes, David Andreu

Direct kinetic assay of interactions between small peptides and immobilized antibodies using a surface plasmon resonance biosensor.

Journal of Immunological Methods, Vol.259,
Pages 217-230, 2002

Paula Gomes, Ernest Giralt, Wendy F. Ochoa, Nuria Verdaguer, David Andreu

Probing degeneracy in antigen-antibody recognition at the immunodominant site of foot-and-mouth disease virus.

Journal of Peptide Research, Vol.59,
Pages 221-231, 2002

Paula Gomes, David Andreu

Binding of small peptides to immobilized antibodies: kinetic analysis using surface plasmon resonance

Current Protocols in Immunology – Ligand-Receptor Interactions in the Immune System
Vol.4, J. E. Coligan (Editor), A. M. Kruisbeek (Editor), D. H. Margulies (Editor), E. M. Shevach (Editor), W. Strober (Editor), R. Coico (Editor), John Wiley & Sons, Nova Iorque,
Pages 18.9.1-18.9.22, 2002

Paula Gomes, Maria A. B. C. S. Oliveira

Métodos Separativos e Espectroscópicos em Química Orgânica

manual de trabalhos práticos para o 3º ano da Licenciatura em Química, Departamento de Química da Faculdade de Ciências do Porto, 2002

Paula Gomes

Química – trabalhos práticos

manual de trabalhos práticos para o 1º ano da Licenciatura em Biologia, Departamento de Química da Faculdade de Ciências do Porto, 2002

Maria J. S. M. P. Araújo, Raquel Castanheiro, Ricardo Ferraz, Rui Moreira, Paula Gomes

Peptide 4-imidazolidinones as drug delivery systems.

Journal of Peptide Science, 8 (Suppl), S207, 2002

Paula Gomes, Ernest Giralt, David Andreu

Antigenicity modulation upon peptide cyclization: application to the GH loop of foot-and-mouth disease virus strain C1-Barcelona.

Vaccine, Vol.19,
Pages 3459-3466, 2001

Dora Pinho, Paula Gomes, C. Freire, Baltazar de Castro

Ground State Modulation in Nickel(III) Chemistry by Controlling Axial Ligation in Complexes with N3O2 Pentadentate Ligands.

European Journal of Inorganic Chemistry, Vol.2001,
Pages 1483-1493, 2001

Esther Blanco, M. García-Briones, A. Sanz-Parra, Paula Gomes, Eliandre de Oliveira, Marí-Luz Valero, David Andreu, Victoria Ley, Francisco Sobrino

Identification of T-Cell Epitopes in Nonstructural Proteins of Foot-and-Mouth Disease Virus.

Journal of Virology, Vol.75,
Pages 3164-3174, 2001

Paula Gomes, Ernest Giralt, David Andreu

Molecular analysis of peptides from the GH loop of foot-and-mouth disease virus C-S30 using surface plasmon resonance: a role for kinetic rate constants.

Molecular Immunology, Vol.37,
Pages 975-985, 2001

Paula Gomes, Ernest Giralt, David Andreu

Biosensor analysis in the improvement of antigenicity of peptides from C-S30 foot-and-mouth disease virus.

Peptides 2000 - Proceedings of the 26th European Peptide Symposium
J. Martinez (Editor), J.-A. Fehrentz (Editor), EDK, Paris,
Pages 639-640, 2001

Paula Gomes,

Química – trabalhos práticos

manual de trabalhos práticos para o 1º ano da Licenciatura em Biologia, Departamento de Química da Faculdade de Ciências do Porto, 2001

Paula Gomes, Ernest Giralt, David Andreu

Surface plasmon resonance biosensing in the study of viral antigenic sites mimicked by synthetic peptides.

Amino Acids, 21(1), 11, 2001

Paula Gomes

Surface plasmon resonance as a tool in the functional analysis of an immunodominant site in foot-and-mouth disease virus

Facultat de Química de la Universitat de Barcelona, 2000

Wendy F. Ochoa, Susana Kalko, Mauricio G. Mateu, Paula Gomes, David Andreu, Esteban Domingo, Ignasi Fita, Nuria Verdaguer

A multiply substituted G–H loop from foot-and-mouth disease virus in complex with a neutralizing antibody: a role for water molecules.

Journal of General Virology, Vol.81,
Pages 1495-1505, 2000

Paula Gomes, Ernest Giralt, David Andreu

Direct single-step surface plasmon resonance analysis of interactions between small peptides and immobilized monoclonal antibodies.

Journal of Immunological Methods, Vol.235,
Pages 101-111, 2000

Maria A. B. C. S. Oliveira, Paula Gomes

Análise Química e Estrutural – Química Orgânica

manual de trabalhos práticos para o 2º ano da Licenciatura em Bioquímica, Departamento de Química da Faculdade de Ciências do Porto, 2000

Maria A. B. C. S. Oliveira, Paula Gomes

Métodos Separativos e Espectroscópicos em Química Orgânica

manual de trabalhos práticos para o 3º ano da Licenciatura em Química, Departamento de Química da Faculdade de Ciências do Porto, 2000

Paula Gomes, Ernest Giralt, David Andreu

Biosensor analysis in the improvement of antigenicity of peptides from C-S30 foot-and-mouth disease virus.

Journal of Peptide Science, 6 (Suppl), S169, 2000

Wendy F. Ochoa, Susana Kalko, Paula Gomes, Ignasi Fita, Nuria Verdaguer

Fab fragment of neutralising monoclonal antibody 4C4 complexed with G-H loop from FMDV.

RCSB Protein Data Bank structure 1EJO, 2000., 2000

Paula Gomes, Ernest Giralt, David Andreu

Surface plasmon resonance screening of synthetic peptides mimicking the immunodominant region of C-S8c1 foot-and-mouth disease virus.

Vaccine, Vol.18,
Pages 362-370, 1999

Paula Gomes

Estudo da síntese de derivados da sulfametazina – potenciais pró-fármacos para a quimioterapia da malária

Faculdade de Ciências da Universidade do Porto, 1996